Pregabalin UK


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Pregabalin is a medication used to treat various conditions such as epilepsy, neuropathic pain, and generalized anxiety disorder. It works by reducing abnormal electrical activity in the brain and slowing down impulses in the nervous system. Pregabalin is sold under the brand name Lyrica and is available in capsule or oral solution form. It is a prescription medication and should only be taken as directed by a healthcare professional.

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What is pregabalin (Lyrica)?

Pregabalin (Lyrica) is in a class of medications called anticonvulsants. Pregabalin works by slowing down impulses in the brain that cause seizures and pain.

Use this drug as ordered by your doctor. Do not use more of it and do not use it more often than prescribed by your doctor. Your doctor may direct you not to take this medication for a certain period of time before an operation or procedure. Follow your doctor’s instructions carefully.

It is a prescription medicine used in adults for the following:

To treat certain types of epilepsy (partial onset seizures) in patients 2 years and older. To help control some types of pain (such as diabetic neuropathy, shingles, postherpetic neuralgia, fibromyalgia). To treat certain types of seizures (partial onset seizures) in patients 1 year and older who have epilepsy and have had no more than 2 partial onset seizures each month during 4 straight months prior to taking this medicine.

How does it work? When is it to be taken?

Clinical studies suggest that pregabalin works by acting on certain parts of the brain and spinal cord. It affects chemicals in the brain which pass messages from one nerve cell to another. By doing this, it increases the amount of serotonin in the brain and also increases activity of two chemicals called gamma aminobutyric acid (GABA) and glycine. It acts differently in different parts of the body. It relaxes the nerves found in your spine and brain which decreases pain perception resulting in pain relief. It also helps in increasing sleep thus enhancing its calming effect on your central nervous system. Pregabalin should be taken once or twice daily depending

Off-Label Uses

Pregabalin has been studied in clinical trials and found effective for:-

– Fibromyalgia pain, tension headaches, and general anxiety disorder. Pregabalin is also commonly used for other types of nerve pain (neuropathic pain) such as diabetic peripheral neuropathy or similar nerve pain following injury

Precaution & Warning

Pregnancy and breast-feeding: Do not use this medication if you are pregnant. If you become pregnant, contact your doctor. There is a potential for serious side effects to an unborn child, particularly in the first trimester of pregnancy. Talk to your doctor about the benefits and risks of using this medication during pregnancy.

  • People with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medication.
  •  If you have AIDS, a history of alcoholism or drug abuse, or if you have or may have liver or kidney problems, talk to your doctor or pharmacist before taking this medicine.
  • This drug can make you drowsy and affect your vision. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.
  • Tell your doctor right away if blurred vision worsens or does not go away.
  • Healthcare professionals are advised to consult the product labeling for dosage form and strength and other information considered relevant by the manufacturers when prescribing telmisartan medoxomil alone and in combination with hydrochlorothiazide for patients aged ≥ 2 years.

Do not stop using gabapentin suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to safely stop using this medication. Your doctor may need to slowly decrease your dose before prescribe you another non-narcotic pain reliever (such as acetaminophen/paracetamol or NSAIDS like ibuprofen).


Pregabalin has not been approved for use in children under the age of 18. However, it may be prescribed off-label by a healthcare provider for certain conditions in children.

The use of Pregabalin during pregnancy should be carefully weighed by a healthcare provider, as there is limited data on its safety in pregnant women. Women who are pregnant or planning to become pregnant should discuss the risks and benefits of taking Pregabalin with their healthcare provider.

Yes, weight gain is a common side effect of Pregabalin. Patients who experience significant weight gain while taking Pregabalin should discuss their options with their healthcare provider.

Pregabalin can be taken with or without food, as directed by a healthcare provider. However, taking it with food may help reduce certain side effects, such as stomach upset.

Yes, sudden withdrawal of Pregabalin can cause withdrawal symptoms, including seizures, anxiety, insomnia, and sweating. Patients should consult with their healthcare provider before discontinuing the medication and should follow a tapering schedule to gradually reduce the dose.


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